Heparinase I for Diagnostics
Heparinase I rapidly and specifically neutralizes both unfractionated heparin as well as low molecular weight heparin, allowing baseline hemostasis to be monitored in the presence of these anticoagulants.
As a result, Heparinase I is incorporated into disposables from a number of leading diagnostic companies, and is in development for additional diagnostic uses.
Heparinase I Diagnostic Uses & Partners |
Activated Clotting Time (ACT) |
May be performed several times during CABG surgery to assess heparin reversal, hemodilution and heparin rebound. |
Hepzyme® |
Hepzyme® may be added to blood samples to reduce test ambiguity when the presence of heparin or low molecular weight heparin is suspected. |
Thromboelastography (TEG) |
May be performed several times during CABG surgery to assess heparin reversal, hemodilution, heparin rebound, platelet function and fibrinolysis. |
Prothrombin Time (PT) |
Heparinase is added to PT cartridges to make them heparin insensitive, for monitoring oral anticoagulation therapy. |
Rotation Thromboelastometry (RT) |
May be performed several times during CABG surgery to assess heparin reversal, hemodilution and heparin rebound. |
Selected Diagnostic Partnerships
![siemens_logo-150x99](https://ibexpharma.com/wp-content/uploads/2017/09/siemens_logo-150x99-2.png)
![abbott-367x100](https://ibexpharma.com/wp-content/uploads/2017/09/abbott-367x100-2.png)
![medtronic-logo-150x99](https://ibexpharma.com/wp-content/uploads/2017/09/medtronic-logo-150x99.png)
![tem_265x100](https://ibexpharma.com/wp-content/uploads/2017/09/tem_265x100-1.png)
![haemonetics_logo-319x100](https://ibexpharma.com/wp-content/uploads/2017/09/haemonetics_logo-319x100.png)