Collagen Type II Cleavage Sandwich Assay (IB-C2C-HUSA™)
Cat. # 60-1007
Cat. # 60-1007

Intended use:
The C2C-HUSA ELISA kit measures cartilage degradation. This assay with specific monoclonal antibodies is primarily designed to detect a type II collagen 45-mer collagenase-generated cleavage fragment commonly found in human urine. In a sandwich assay design the capture mAb is specific for intra-chain sequence and Tracer-HRP mAb is specific for C2C C-terminal neoepitope.
Click here – to download the C2C-HUSA Specification Sheet
Method: ELISA sandwich, 96 wells strip plate
Sample type: Human urine only
Sample volume: 30 µL per replicate
Calibration range: 156 – 5000 pg/mL
Incubation time: 2 hours
Species: Human. Not suitable for equine use. Utility in other species has not been established
Cross-reaction: No cross-reaction with corresponding neoepitope peptides derived from collagen type I and collagen type III is detected